Embryonic development in a given species is orchestrated by genes regulating growth and differentiation in a stereotyped and conserved manner, resulting in embryos of consistent size and shape. Several signaling pathways, including that of Sonic Hedgehog (SHH), have been implicated in these processes. Recent experiments with Gas1 indicate that it may act as a growth-inducing gene, challenging its previous function as a gene specifically involved in growth arrest. Moreover, GAS1, a GPI-linked membrane protein, can bind SHH, suggesting an interacting link (...) between growth and patterning through SHH and GAS1.(1-4) BioEssays 24:22–26, 2002. © 2002 John Wiley & Sons, Inc. (shrink)

Introduction: The use of human samples in genomic research has increased ethical debate about informed consent (IC) requirements and the information that subjects should receive regarding the results of the research. However, there are no quantitative data regarding researchers’ attitudes about these issues. Methods: We present the results of a survey of 104 US and 100 Spanish researchers who had published genomic epidemiology studies in 61 journals during 2006. Results: Researchers preferred a broader IC than the IC they had actually (...) obtained in their published papers. US authors were more likely than their Spanish colleagues to support obtaining a broad IC, covering either any future research project or any projects related to a group of diseases (67.6% vs 43%; adjusted OR = 4.84, 95% CI, 2.32 to 10.12). A slight majority of researchers (55.8%) supported informing participants about individual genomic results only if the reliability and clinical validity of the information had been established. Men were more likely than women to believe that patients should be informed of research results even if these conditions were not met (adjusted OR = 2.89, 95% CI = 1.46 to 5.72). Conclusions: This study provides evidence of a wide range of views among scientists regarding some controversial ethical issues related to genomic research, suggesting the need for more study, debate and education. In the interim, journals might consider including the investigators’ policies regarding these ethical issues in the papers they publish in the field of genomic epidemiology. (shrink)

Both traditional accounts of hope and some of their recent critics analyze hope exclusively in terms of attitudes that a hoper bears towards a hoped-for prospect, such as desire and probability assignment. I argue that all of these accounts misidentify cases of despair as cases of hope, and so misconstrue the nature of hope. I show that a more satisfactory view is arrived at by noticing that in addition to the aforementioned attitudes, hope involves a characteristic attitude towards an external (...) factor, on whose operation the hoper takes the prospect's realization to depend causally. (shrink)

ABSTRACT Recently, the hypothesis that purely evaluative disputes are metalinguistic negotiations has gained traction. I resist a strong version of that hypothesis, and argue that some of those disputes are not metalinguistic negotiations. To defend that claim, I argue that metalinguistic negotiations have three linguistic properties that some purely evaluative disputes lack. First, in a metalinguistic negotiation it is felicitous to embed the dispute-initial statement under the subjective attitude verb consider; second, a speaker can reply to that initial statement by (...) using a metalinguistic comparative; and, third, such negotiations address metalinguistic questions under discussion. Some purely evaluative disputes lack these properties, which suggests that they are not metalinguistic negotiations. (shrink)

While opinions on the semantic analysis of generics vary widely, most scholars agree that generics have a quasi-universal flavor. However, there are cases where generics receive what appears to be an existentialinterpretation. For example, B's response is true, even though only theplatypus and the echidna lay eggs: (1) A: Birds lay eggs. B: Mammals lay eggs too. In this paper I propose a uniform account of the semantics of generics,which accounts for their quasi-existential readings as well as for their more (...) familiar quasi-universal ones. Generics are focus-sensitiveoperators: their domain is restricted by a set of alternatives, which may be provided by focus. I claim that, unlike otherfocus-sensitive operators, generics may, but do not have to, associate with focus. When alternatives are introduced, either by focus or by other means, generics get their usual quasi-universal readings. But when no alternatives are introduced, quasi-existential readings result.I argue that generics, unlike adverbs of quantification, do not introduce tripartite structures directly, but are initially interpreted as cases ofdirect kind predication. Only when this interpretation fails to make sense, the phonologically null generic quantifier is derived, and tripartite structures result. This two-level interpretation has the effect that while adverbs of quantification require focus to determine which elements go to the restrictor and which to the nuclear scope, and hence must associate with focus, generics do not, and hence may fail to associate with focus, resulting in quasi-existential readings. (shrink)

This paper defends a rigorous reading of Hume’s critiques of arguments for the existence of God and of the belief in God against interpretations that endorse Humean theism, deism, and fideism. The latter include Donald Livingston’s theist reading, J. C. A. Gaskin’s “attenuated deism” reading, and Edward Kanterian’s “humble fideism” reading. I also examine whether Hume’s rejections of a positive theology commit him to agnosticism or atheism. My innovative challenge to such conclusions maintains that, while elements of both agnosticism and (...) atheism are found in Hume, these denote, respectively, a methodology and an incidental implication of his philosophy. But neither sufficiently captures his constructive vision for a society, individual psychology, and system of knowledge guided by naturalist principles and aims. For this, an alternate conception is needed that describes Hume’s philosophy of religion beyond mere atheism. (shrink)

In spite of the burgeoning philosophical literature on human dignity, Stephen Darwall's second-personal account of the dignity of persons has not received the attention it deserves. This article investigates Darwall's account and argues that it faces a dilemma, for it succumbs either to a problem of antecedence or to the wrong kind of reasons problem. But this need not mean one should reject a second-personal account. Instead, I argue that an alternative second-personal conception, one I will call relational, promises to (...) solve the dilemma by avoiding both the problem of antecedence and the wrong kind of reasons problem. More generally, distinguishing these two second-personal conceptions of the dignity of persons is important to enrich the available philosophical accounts of human dignity. (shrink)

In this paper I explore elements from Kant’s philosophy of right to develop a relational account of the wrong of poverty. Poverty is a relational wrong because it involves relations of problematic dependence, inequality, and humiliation. Such relations infringe the rights to freedom and equality of the poor. And the called-for response is one of public recognition and protection of the rights of the poor. This position means we must radically reconceptualize our individual duties to the poor: not _private beneficence_, (...) but _private remedies for public failures_. (shrink)

Claiming rights against one another is a perfectly familiar phenomenon. We express the elementary thought you cannot do that to me in a variety of ways. And yet, in spite of the perfect familiarity of this phenomenon, the two standard philosophical theories of rights face notorious difficulties in accounting for it. My aim in this paper is to introduce a distinctive, second-personal account of rights. I will call this the independence theory of rights, the view that rights are specifications of (...) a basic right to independence against another. And I will argue that by taking as basic the second-personal thought you cannot do that to me the independence theory best illuminates the basic phenomenon of having rights against one another. (shrink)

Cognitive penetration of perception, broadly understood, is the influence that the cognitive system has on a perceptual system. The paper shows a form of cognitive penetration in the visual system which I call ‘architectural’. Architectural cognitive penetration is the process whereby the behaviour or the structure of the perceptual system is influenced by the cognitive system, which consequently may have an impact on the content of the perceptual experience. I scrutinize a study in perceptual learning that provides empirical evidence that (...) cognitive influences in the visual system produce neural reorganization in the primary visual cortex. The type of cognitive penetration can be synchronic and diachronic. (shrink)

I defend a metalinguistic account of Mates's puzzle: sentences where synonymous expressions cannot be substituted salva veritate. If Andrea thinks that attorneys are different from lawyers, and she thinks that Fiona is the former but not the latter, we may hesitate to substitute ‘lawyer’ for ‘attorney’ in ‘Andrea believes that Fiona is an attorney’, even though ‘lawyer’ and ‘attorney’ are synonymous. I argue that these sentences report de re beliefs about linguistic expressions, thereby blocking such substitutions, and I offer a (...) compositional derivation of their meaning. (shrink)

I argue against the view that metalinguistic usage is a form of conversational implicature. That view, suggested by Thomasson (Anal Philos 57(4):1-28, 2016) and Belleri (Philos Stud 174(9):2211–2226, 2017), has been most recently fleshed out by Mankowitz (Synthese 199:5603–5622, 2021). I provide two types of criticism to the implicature view. From an empirical point of view, metalinguistic usage differs in key respects from standard cases of conversational implicature. From a conceptual standpoint, I argue that the calculation algorithm provided by the (...) implicature view makes undesirable predictions. Although my main objective is negative, I end the paper by sketching an alternative neo-Stalnakerian view of metalinguistic usage, that can be gathered from work by Barker (Linguist Philos 25(1):1–36, 2002; Inquiry 56(2–3):240–257, 2013) and others. (shrink)

How should we think about apparent conflicts of moral rights? I defend a non-balancing and holistic specification model: non-balancing because moral rights have absolute deontic stringency regardless of any balance of independent values; holistic because the content of moral rights is limited only by that of other moral rights. Holistic Specification, as I call the model, offers a principled, non-consequentialist explanation of exceptions to moral rights. Moreover, Holistic Specification explains why moral rights matter to practical thought while rendering remedial duties (...) less mysterious. (shrink)

It has been argued that moral assertions involve the possession, on the part of the speaker, of appropriate non-cognitive attitudes. Thus, uttering ‘murder is wrong’ invites an inference that the speaker disapproves of murder. In this paper, we present the result of 4 empirical studies concerning this phenomenon. We assess the acceptability of constructions in which that inference is explicitly canceled, such as ‘murder is wrong but I don’t disapprove of it’; and we compare them to similar constructions involving ‘think’ (...) instead of ‘disapprove’—that is, Moore paradoxes (‘murder is wrong but I don’t think that it is wrong’). Our results indicate that the former type of constructions are largely infelicitous, although not as infelicitous as their Moorean counterparts. (shrink)

One of the most controversial and currently developed lines of research in philosophy of biology is that in which philosophers investigate pre-Darwinian assumptions that would still be present at the base of other philosophical sub-disciplines, such as ethics, epistemology, philosophy of language, etc. This type of inquiry, which I will call here “meta-philosophical interrogation,” can be thought as a complementary approach to the epistemological one, which allows us to broaden the critical approach of the discipline in question. The objective of (...) this article will be to analyze the characteristics of the “meta-philosophical interrogation” and to argue about its legitimacy as a way of inquiry proper to the philosophy of biology. (shrink)

One of the most controversial and currently developed lines of research in philosophy of biology is that in which philosophers investigate pre-Darwinian assumptions that would still be present at the base of other philosophical sub-disciplines, such as ethics, epistemology, philosophy of language, etc. This type of inquiry, which I will call here “meta-philosophical interrogation,” can be thought as a complementary approach to the epistemological one, which allows us to broaden the critical approach of the discipline in question. The objective of (...) this article will be to analyze the characteristics of the “meta-philosophical interrogation” and to argue about its legitimacy as a way of inquiry proper to the philosophy of biology. (shrink)

p. cm. — (Zeuthen lecture book series) Includes bibliographical references (p. ) and index. ISBN 0-262-18187-8 (hardcover : alk. paper). — ISBN 0-262-68100-5 (pbk. : alk. paper) 1. Decision-making. 2. Economic man. 3. Game theory. 4. Rational expectations (Economic theory) I. Title. II. Series.

In addition to the familiar cardinal and proportional readings of many and few, there is yet another interpretation, the relative proportional reading. This reading, unlike the ordinary absolute proportional reading, is not conservative. Under the relative reading, 'Many ψs are φs' is true just in case the proportion of φs among ψs is greater than the proportion of φs among members of contextually given alternatives to ψ. I provide a definition of proportional readings that reduces the differences between absolute and (...) relative interpretations to the value of a single parameter.I argue that relative readings are not restricted to many and few, but are also exhibited by the adverbs often and seldom, and by generics. Interpretations of determiners that have been treated as "focus-affected readings," interpretations of adverbs of quantification that have been treated as "pure frequency readings," and interpretations of generics which have been claimed to be cases of "reverse interpretation" or "direct kind predication" are, in fact, instances of relative readings.A: Army reserve service is especially hard on people who own a small business.Q: Do many small-business owners serve in your regiment?A: I don't know what it's like in other regiments –Q: I am not asking you about other regiments.A: I know, but relatively speaking . . .(Interview on Israel Army Radio, June 8th, 2001). (shrink)

This paper investigates the conceptual and empirical possibility of non-executed, non-conscious proximal intentions, i.e., non-conscious proximal intentions to act that do not turn into a final act, but perhaps are vetoed or overcome by an alternative action. It constructs a conceptual framework in which such cases are justifiably considered ‘proximal intentions’. This is achieved by combining Alfred Mele’s notion of non-conscious proximal intentions together with the notion of trying or striving taken from Brian O’Shaughnessy’s model of action. With this framework (...) in hand we analyze empirical electroencephalography (EEG) findings regarding ‘change of intention’ scenarios. Prior to EEG development (and other brain imaging techniques), one would never consider non-executed, non-conscious proximal intentions a case of intention at all. However, with technological and interpretable development of EEG, a whole group of so called ‘intentions’ appears, and the main aim of the paper is to justify this expanded usage. (shrink)

This article provides current Schwartz Values Survey data from samples of business managers and professionals across 50 societies that are culturally and socioeconomically diverse. We report the society scores for SVS values dimensions for both individual- and societallevel analyses. At the individual- level, we report on the ten circumplex values sub- dimensions and two sets of values dimensions. At the societal- level, we report on the values dimensions of embeddedness, hierarchy, mastery, affective autonomy, intellectual autonomy, egalitarianism, and harmony. For each (...) society, we report the Cronbach' s? statistics for each values dimension scale to assess their internal consistency as well as report interrater agreement analyses to assess the acceptability of using aggregated individual level values scores to represent country span sp. (shrink)

Through hypothetical scenarios, this paper analyses whether machine learning (ML) could resolve one of the main shortcomings present in Christopher Boorse’s Biostatistical Theory of health (BST). In doing so, it foregrounds the boundaries and challenges of employing ML in formulating a naturalist (i.e., prima facie value-free) definition of health. The paper argues that a sweeping dataist approach cannot fully make the BST truly naturalistic, as prior theories and values persist. It also points out that supervised learning introduces circularity, rendering it (...) incompatible with a naturalistic perspective. Additionally, it underscores the need for pre-existing auxiliary theories to assess results from unsupervised learning. It emphasizes the importance of understanding the epistemological entanglements between data and data processing methods to manage expectations about what data patterns can predict. In conclusion, the paper argues against delegating the final authority for defining complex concepts like health to AI systems, as it necessitates ethical judgment and capacities for deliberation that AI currently lacks. It also warns against granting creators and deployers of AI systems the discretionary authority to determine these definitions outside the wider social discussion, advocating for ongoing public engagement on normative notions. Failure to do so risks limiting individuals and collectives’ ability to shape a just digital future and diminishes their fundamental epistemic agency. (shrink)

Studies investigating the COVID-19 pandemic from a psychological point of view have mostly focused on psychological distress. This study adopts the framework of existential positive psychology, a second wave of positive psychology that emphasizes the importance of effective coping with the negative aspects of living in order to achieve greater wellbeing. Trait emotional intelligence (trait EI) can be crucial in this context as it refers to emotion-related personality dispositions concerning the understanding and regulation of one’s emotions and those of others. (...) The present study investigated the relationship between trait EI and both wellbeing and psychological distress (i.e., depression, anxiety, and stress), while exploring the mediating role of meaning-centered coping (proactive transformative strategies based on meaning in life) and maladaptive coping (i.e., behavioral disengagement and self-blame) during the first few months of the COVID-19 pandemic. A sample of 326 Lebanese adults completed measures of trait EI, wellbeing, psychological distress, coping, and meaning-centered coping. Results showed a strong positive correlation between trait EI and meaning-centered coping. Trait EI also correlated positively with wellbeing and negatively with psychological distress. Structural equation modeling showed that meaning-centered coping partially mediated the relationship between trait EI and wellbeing. Maladaptive coping fully mediated the relationship between trait EI and psychological distress. Findings indicate that trait EI is positively related to dealing with a stressful situation such as the pandemic in positive ways at both the cognitive level, by reformulating the situation to see something valuable in it, and behavioral level, by being proactive about it. Trait EI was positively linked to seeing the situation as an opportunity for personal growth, finding personal meaning in this situation, maintaining an attitude of hope and courage, and acting more responsibly with one’s self and others during the current crisis. In turn, this coping formula was related to lower psychological distress and improved mental health. These results are consistent with the existential positive psychology framework and can inform implementation programs and policies aiming at raising awareness and promoting healthy and successful coping during the pandemic. (shrink)

This paper presents an updated reading of the Platonicconfrontation of Republic I, II, III and X with poets. Specifically, opposing the traditional readings that tend to focus on the ontological plane, this writing will investigate the Platonic warning about the plasticity and, consequently, the functionality of images. It is proposed as a contribution to redirect the criticism of poets to one of the central topics of Rep., the tension between appearance and reality, to account for their connection with the forms (...) of deception in πρᾶξις. In this sense, the objective is to show that the capacity of myths to form character and the social imaginary, as a dispositive of power, is anchored in the types of access and the ways of knowing that guide πρᾶξις. This will then allow us to rethink a current topic: the capacity of εἴδωλα, in a broad sense, to produce subjects and social values, as well as the ways of practical knowledge. (shrink)

Doernberg and Truog (2023) present a thoughtful analysis of the ethical tensions that arise from physicians increasingly occupying “multiple roles in healthcare”1 I take no issue with the classific...

The aim of this article is twofold: first, to identify and address three central divisions in the field of authentic education that introduce ambiguity and at times inconsistencies within the field of authentic education. These divisions concern a) the relationship between autonomy and authenticity; b) the division between the two basic attitudes towards ‘care’ in the authenticity literature, and; c) the well-worn division between objective and subjective realms of knowledge and identity construction. Addressing these divisions through Charles Taylor's distinction between (...) active and passive aspects of authenticity, I believe, will lead to a better understanding of the main issues involved in conceptualising and applying authenticity-based education. Second, to present what I call The Postconventional Authentic Relation-to-Self as a basis for overcoming and reconciling the above divisions. I shall conclude by providing some examples of the way the perspective envisioned by PARTS can be applied to educational practices. (shrink)

In this article, I examine the issue of the alleged circularity in the determination of homologies within cladistic analysis. More specifically, I focus on the claims made by the proponents of the dynamic homology approach, regarding the distinction (sometimes made in the literature) between primary and secondary homology. This distinction is sometimes invoked to dissolve the circularity issue, by upholding that characters in a cladistic data matrix have to be only primarily homologous, and thus can be determined independently of phylogenetic (...) hypotheses, by using the classical Owenian criteria (for morphological characters) or via multiple sequence alignment (for sequence data). However, since in the dynamic approach, sequence data can be analyzed without being pre-aligned, proponents have claimed that the distinction between primary and secondary homology has no place within cladistics. I will argue that this is not the case, since cladistic practice within the dynamic framework does presuppose primary homology statements at a higher level. (shrink)

Recent research has shown that the superlative quantifiers at least and at most do not have the same type of truth conditions as the comparative quantifiers more than and fewer than. We propose that superlative quantifiers are interpreted at the level of speech acts. We relate them to denegations of speech acts, as in I don’t promise to come, which we analyze as excluding the speech act of a promise to come. Calling such conversational acts that affect future permissible speech (...) acts “meta-speech acts,” we introduce the meta-speech act of a GRANT of a proposition as a denial to assert the negation of that proposition. Superlative quantifiers are analyzed as quantifiers over GRANTS. Thus, John petted at least three rabbits means that the minimal number n such that the speaker GRANTs the proposition that John petted n rabbits is n = 3. We formalize this interpretation in terms of commitment states and commitment spaces, and show how the truth conditions that are derived from it are partly entailed and partly conversationally implicated. We demonstrate how the theory accounts for a wide variety of distributional phenomena of superlative quantifiers, including the contexts in which they can be embedded. (shrink)

I discuss conceptual confusions shared by deep ecologists over such questions as gender, essentialism, normative dualism, and eco-centrism. I conclude that deep ecologists have failed to grasp both the epistemological challenge offered by ecofeminism and the practical labor involved in bringing about social change. While convergencies between deep ecology and ecofeminism promise to be fruitful, these are celebrated in false consciousness, unless remedial work is done.

Most solutions to the sorites reject its major premise, i.e. the quantified conditional . This rejection appears to imply a discrimination between two elements that are supposed to be indiscriminable. Thus, the puzzle of the sorites involves in a fundamental way the notion of indiscriminability. This paper analyzes this relation and formalizes it, in a way that makes the rejection of the major premise more palatable. The intuitive idea is that we consider two elements indiscriminable by default, i.e. unless we (...) know some information that discriminates between them. Specifically, following Rough Set Theory, two elements are defined to be indiscernible if they agree on the vague property in question. Then, a is defined to be indiscriminable from b if a is indiscernible by default from b . That is to say, a is indiscriminable from b if it is consistent to assume that a and b agree on the relevant vague property. (shrink)

Hostages have become an important political and security issue in the context of conflicts in the Middle East and in Africa. The work of Marcel Mauss helps us to shed a new light on this phenomenon, which today is portrayed in negative terms as a major violation of fundamental universal rights such as the right to liberty. In The Gift, however, Mauss refers to the granting of hostages as “acts of generosity.” In line with Mauss’ approach, I consider hostageship as (...) a “total social phenomenon,” combining politics, law, and economics, in both domestic and global settings, which reveals structural political and social questions that need to be addressed. The article highlights the role that hostages fulfilled as “gifts” in premodern international relations when hostages were granted and not taken as they are today. I underline the role they notably performed as elements of proto-diplomacy. I show the reasons why the function of hostages has changed over time by underlining the importance of the later Middle A... (shrink)

The article argues for the social production of curiosity. Due its motivating characteristic, curiosity is reconceptualized as an epistemic drive which organizes the social production of knowledge under given socio-historical and local-cultural circumstances. First, historical, philosophical, and sociological literature is reviewed to give a context for the argument. Then a theoretical apparatus is developed considering the emergence, development, and impact of epistemic drives which serves as a foundation for empirical analysis. The second part demonstrates applicability by discussing the problem of (...) economic incentives in scientific research. I argue that scientific projects with little to none immediate economic return have a significant disadvantage in acquiring funding which in turn impacts the mobilization of curiosity in their field. A tendency which systematically yields a disproportionate distribution of knowledge. In conclusion, the article suggests the usefulness of the epistemic drive notion in understanding curiosity as a sociological object. (shrink)

In this paper we show that focus structure determines the interpretation of bare plurals in English: topic bare plurals are interpreted generically, focused bare plurals are interpreted existentially. When bare plurals are topics they must be specific, i.e. they refer to kinds. After type-shifting they introduce variables which can be bound by the generic quantifier, yielding characterizing generics. Existentially interpreted bare plurals are not variables, but denote properties that are incorporated into the predicate.The type of predicate determines the interpretation of (...) its bare plural subject. The individual/stage-level distinction, though important, is not sufficient: since only arguments can be topics, only those stage-level predicates which have locative arguments can have existential bare plural subjects.Certain verbs (e.g., hate) fail to incorporate their bare plural objects; therefore no existential reading of the object is available. We provide a novel solution to this puzzle based on the following two claims: (i) incorporated bare plurals do not introduce discourse referents; (ii) nonincorporating verbs are presuppositional. (shrink)

En el marco de los estudios actuales sobre la relación entre teoría y práctica de mímesis en Platón, el objetivo es indagar la caracterización [ethopoiía] platónica de Sócrates. Para tal fin, por un lado, se analiza la tematización de la caracterización en los Progymnásmata para mostrar su función y el lugar que ocupa Platón en esta tradición. Por otro lado, se estudian algunos pasajes clave de Apología de Sócrates y República I para echar luz sobre la composición narrativa, mímesis, y, (...) a través de ella, intentar dar cuenta del quehacer filosófico en la caracterización socrática. La hipótesis es que la opción por el diálogo está ligada no solo al modo de comprender, sino también al modo de transmitir el saber filosófico, y que, en tal marco, el personaje Sócrates encarna un tipo de saber hacer o disposicional. Este tipo de saber no sería reductible a proposiciones, de manera que la opción por el diálogo cumpliría una función no meramente estilística, sino fundamentalmente propedéutico-filosófica. (shrink)

The superlative quantifiers, at least and at most, are commonly assumed to have the same truth-conditions as the comparative quantifiers more than and fewer than. However, as Geurts & Nouwen have demonstrated, this is wrong, and several theories have been proposed to account for them. In this paper we propose that superlative quantifiers are illocutionary operators; specifically, they modify meta-speech acts.Meta speech-acts are operators that do not express a speech act, but a willingness to make or refrain from making a (...) certain speech act. The classic example is speech act denegation, e.g. I don't promise to come, where the speaker is explicitly refraining from performing the speech act of promising What denegations do is to delimit the future development of conversation, that is, they delimit future admissible speech acts. Hence we call them meta-speech acts. They are not moves in a game, but rather commitments to behave in certain ways in the future. We formalize the notion of meta speech acts as commitment development spaces, which are rooted graphs: The root of the graph describes the commitment development up to the current point in conversation; the continuations from the root describe the admissible future directions.We define and formalize the meta-speech act GRANT, which indicates that the speaker, while not necessarily subscribing to a proposition, refrains from asserting its negation. We propose that superlative quantifiers are quantifiers over GRANTs. Thus, Mary petted at least three rabbits means that the minimal number n such that the speaker GRANTs that Mary petted n rabbits is n = 3. In other words, the speaker denies that Mary petted two, one, or no rabbits, but GRANTs that she petted more.We formalize this interpretation of superlative quantifiers in terms of commitment development spaces, and show how the truth conditions that are derived from it are partly entailed and partly conversationally implicated. We demonstrates how the theory accounts for a wide variety of phenomena regarding the interpretation of superlative quantifiers, their distribution, and the contexts in which they can be embedded. (shrink)

The adequacy of Elliott Sober’s analogy between classical mechanics and evolutionary theory—according to which both theories explain via a zero-force law and a set of forces that alter the zero-force state—has been criticized from various points of view. I focus here on McShea and Brandon’s claim that drift shouldn’t be considered a force because it is not directional. I argue that there are a number of different theses that could be meant by this, and show that one of those theses—the (...) idea that drift cannot bias populations to be taken somewhere in the evolutionary space from one generation to the next—is actually false. Not only has this thesis been implicitly assumed in the discussion of the force analogy thus far, but it is also commonly found in a wider range of philosophical and biological texts. I argue that correcting this view, and the usual images associated with it, will thereby bring heuristic benefits that impact the force analogy discussion, but that also go beyond it. (shrink)

The recruitment of respondents belonging to ethnic minorities poses important challenges in social and health research. This paper reflects on the enablers and barriers to recruitment that we encountered in our research work with persons belonging to ethnic minorities. Additionally, we applied the Matching Model of Recruitment, a theoretical framework concerning minority recruitment, to guide our reflection. We also explored its applicability as a research design tool. In assessing our research experience, we learned that minority recruitment in social and health (...) research is influenced by the social context of all key players involved in the research. Also, there are enablers and barriers within that social context facilitating or delaying the recruitment process. The main enablers to recruit respondents belonging to ethnic minorities include working with community agencies and gatekeepers who share a common vision with researchers and the latter’s ability to gain the trust of potential respondents. The main barriers include demanding too much from these same community agencies and gatekeepers and ignoring factors that could delay the completion of the research. Although we found the Matching Model of Recruitment to be an effective tool in assessing the processes of recruiting respondents belonging to ethnic minorities, further empirical research is needed to explore its usefulness during the research planning phase. (shrink)

In this article, I develop three conceptual innovations within the area of formal metatheory, and present a computer program, called Reconstructor, that implements those developments. The first development consists in a methodology for testing formal reconstructions of scientific theories, which involves checking both whether translations of paradigmatically successful applications into models satisfy the formalisation of the laws, and also whether unsuccessful applications do not. I show how Reconstructor can help carry this out, since it allows the end-user to specify a (...) formal language, input axioms and models formulated in that language, and then ask if the models satisfy the axioms. The second innovation is the introduction of incomplete models (for which the denotation of some terms is missing) into scientific metatheory, in order to represent cases of missing information. I specify the paracomplete semantics built into Reconstructor to deal with sentences where denotation failures occur. The third development consists in a new way of explicating the structuralist notion of a determination method, by equating them with algorithms. This allows determination methods to be loaded into Reconstructor and then executed within a model to find out the value of a previously non-denoting term (i.e. it allows the formal reconstruction to make predictions). This, in turn, can help test the reconstruction in a different way. Finally, I conclude with some suggestions about additional uses the program may have. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy and Literature 26.2 (2002) 260-272 [Access article in PDF] Tragic Conflict and Greatness of Character Ariel Meira IT IS A SURPRISING FACT that some of our best literary examples of greatness of character are of persons acting in a way that involves them in a terrible burden of guilt. As spectators we perceive Oedipus, in Sophocles's Oedipus the King, 1 as one who upon discovering the identity (...) of his father and mother affirms that he bears guilt for killing the former and committing incest with the latter, and we typically concur in some vague way with his affirmation. 2 We do not, after all, think that his affirmation is merely the consequence of some confusion about morals on his part, and that he would have been more justified in treating his discovery with a light conscience. Furthermore, it seems that our conception of his greatness is intimately bound up with our being acquainted with him as someone who acted so as to render himself profoundly guilty in this way. What is paradoxical is that moral taint would be expected to reduce our admiration for a character and our attribution of greatness to it. Why then should noteworthy paradigms of greatness of character be morally tainted characters? Can we make sense of the idea that some kinds of guiltiness might be constitutive of greatness of character?As it is well-known, Aristotle says that in order for a tragedy best to achieve its desired effect, it should portray a protagonist "who is not pre-eminent in moral virtue, who passes to bad fortune not through vice or wickedness, but because of some hamartia...." 3 The term "hamartia" is variously translated as "piece of ignorance," "miscalculation," and "error of judgment," but as O. B. Hardison notes, it must be treated as designating a moral flaw, because it renders the protagonist [End Page 260] less than "pre-eminent in moral virtue." 4 However, even if the term is interpreted as covering what I have described as the moral taint associated with greatness of character, it should be clear that Aristotle does not provide here an answer to my question. At best he can be viewed as explaining why morally tainted characters of this sort are crucial to achieving tragic effect. He is not explaining how it is that such characters can be viewed as paradigms of greatness.I propose not to treat this paradox in its most general form, but rather by confining my attention to an interesting subclass of cases. What I have in mind are cases in which a protagonist finds himself or herself in what I shall call circumstances of tragic conflict. Such circumstances determine that a choice must be made between two (or perhaps more) courses of action, even though each of the courses involves the violation of an important moral claim, or the destruction of a crucial value. As spectators or readers, we typically perceive the protagonist as emerging with a heavy burden of guilt (much in the way noted above regarding Oedipus), and we recognize that he or she was bound to emerge guilty, no matter which course of action would have been chosen. Cases such as that of Agamemnon (bearing guilt for the sacrifice of his daughter Iphigenia in Aeschylus's Agamemnon), 5 of Jephthah (again bearing guilt for the sacrifice of his daughter, in Judges 11), 6 and of Orestes (bearing guilt for the murder of his mother Clytemnestra in Euripides's Orestes) 7 belong quite uncontroversially to this subclass. 8These protagonists make difficult choices, and carry them out with courage and resolution, qualities which explain to some extent our perception of them as possessing greatness of character. But in making their choice, they necessarily render themselves guilty, whether or not they have made the correct choice (assuming there is a correct choice in the circumstances). And we sense that suffering the peculiarly poignant pain which accompanies their guilty action is at least partly constitutive of their greatness. Clearly, we are faced again with the paradox of the association of guilt with greatness of character.In... (shrink)

Resumen: En este ensayo desarrollo una crítica al modelo de justicia multicultural de Will Kymlicka, con el propósito de establecer las bases para el desarrollo de un multiculturalismo crítico. El argumento se ordena de la siguiente forma. En la primera sección analizo la teoría de los derechos especiales de Kymlicka e identifico el valor liberal central al que estos responden, la autonomía individual. En la segunda sección examino el fundamento igualitarista de la suerte de su teoría de los derechos especiales. (...) En la tercera sección elaboro una crítica general a la justicia multicultural liberal desarrollando un argumento para politizar los reclamos de los pueblos indígenas para el acceso a su cultura. Argumento que el trato justo de las minorías indígenas requiere reconocer su autodeterminación política.: In this essay I develop a critique of Will Kymlicka’s model of multicultural justice, with the purpose of laying down the foundations for a critical multiculturalism. The argument is ordered in the following way. In the first section I analyse Kymlicka’s theory of special rights and identify the central liberal value to which they respond: individual autonomy. In the second section I examine the luck egalitarian foundations of Kymlicka’s theory of special rights. In the third section, I elaborate a general critique to liberal multicultural justice, developing an argument to politicize the claims of indigenous peoples to access to their culture. Basically I argue that the just treatment of indigenous minorities requires recognizing their political self-determination. (shrink)

The paper argues that four-dimensionalism is incompatible with the existence of additively cumulative properties, including mass, volume, and electrical charge. These properties add up over disjoint objects: for example, the mass of a whole composed of two disjoint objects is a sum of the individual masses of the objects. The difficulty with such properties for four-dimensionalism stems from the way this theory makes persistence depend on the existence of disjoint objects at disjoint times. I consider various possible responses to this (...) difficulty and conclude that they all fail. (shrink)